Focused Ultrasound Foundation Supports Preclinical Study

FUSF image

The Focused Ultrasound (FUS) Foundation has awarded funding to support the Preclinical Brain Project Focused Ultrasound Promotes Blood-Brain Barrier Opening and Delivery of GB13 to Pediatric High-Grade Gliomas. The collaborative effort is between Targepeutics (co-PI Randy Schrecengost PhD, Chief Scientific Officer) and the University of Colorado (co-PIs Adam Green MD, Pediatric Neuro-oncologist and Mark Borden PhD, Professor of Biomedical Engineering).  The one year project generously supports proof-of-concept studies to determine if FUS is a viable administration option for delivery of GB13 to pediatric brainstem tumors, such as diffuse midline glioma (DMG). FUS is a non-invasive method that can focally disrupt the blood-brain barrier for short periods of time, which allows therapies to reach intracranial targets. The award was recently announced by FUS Foundation here:

https://www.fusfoundation.org/posts/research-awards-update-three-preclinical-projects-initiated-in-the-fourth-quarter-of-2024/